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Cephalexin belongs to a class of antibiotics called cephalosporins. Keflex is a semi-synthetic cephalosporin antibiotic for oral administration. Patients taking other cephalosporin antibiotics can not take additional cephalosporin antibiotics as this is likely to result in an overdose. Patients with known allergy to the cephalosporin group of antibiotics. Keflex is a semi-synthetic cephalosporin antibiotic for oral administration. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection. Side effects can be serious.